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团队成员

曹世诺



1、个人简历
曹世诺,男,博士,助理研究员,基础免疫创新团队,研究领域(弓形虫感染相关蛋白分泌机制对其入侵及生长的调控作用),主持国家自然科学基金项目1项,发表SCI论文53篇,其中以第一作者及共同第一作者发表SCI论文15篇。


 
2、联系方式
(1)研究方向:动物寄生虫及其分子生物学
(2)电话:0451-51051760
(3)邮箱:caoshinuo@caas.cn
(4)通讯地址:黑龙江省哈尔滨市香坊区哈平路678号
 
3、教育经历 
2002.09-2006.06  延边大学 ,生物技术专业 ,学士
2006.09-2009.06  延边大学 ,  预防兽医专业, 硕士
2010.09-2013.06  日本带广畜产大学,  畜产卫生专业,博士
 
4、工作经历
2013.04-2013.09   日本国立原虫病研究中心, 博士后
2013.10-2015.10   日本国立原虫病研究中心 ,  日本学术振兴会(JSPS)特别研究员
2015.10-至今         中国农科院哈尔滨兽医研究所, 助理研究员
 
5、承担项目
   (1) 国家自然科学基金:TgHSP101对弓形虫蛋白跨纳虫空泡膜转运及其复制的调控作用(31702230), 24万元;
 
6、代表论文与著作
   (1)  Shinuo Cao, Nali Du, Heming Chen, Yu Pang, Zhaoxia Zhang, Jun Zheng,Honglin Jia*. Toxoplasma gondii Clp family protein: TgClpB1 plays a crucial role in thermotolerance. Oncotarget. 2017, 12(12):e0189383.
   (2)  Mo Zhou#, Shinuo Cao#, Ferda Sevinc, Mutlu Sevinc, Onur Ceylan, Sepil Ekici, Charoonluk Jirapattharasate, Paul Franck Adjou Moumouni, Mingming Liu, Guanbo Wang, Aiko Iguchi, Patrick Vudriko, Hiroshi Suzuki, Xuenan Xuan*,Molecular detection and genetic characterization of Babesia, Theileria and Anaplasma amongst apparently healthy sheep and goats in the central region of Turkey. Ticks and Tick-borne Diseases, 2017, 8(2): 246-252.
   (3)  Mo Zhou#, Shinuo Cao#, Ferda Sevinc, Mutlu Sevinc, Onur Ceylan, Mingming Liu, Guanbo Wang, Paul Franck Adjou Moumouni, Charoonluk Jirapattharasate, Hiroshi SuzukI, Yoshifumi Nishikawa, Xuenan Xuan*, Enzyme-linked immunosorbent assays using recombinant TgSAG2 and NcSAG1 to detect Toxoplasma gondii and Neospora caninum-specific antibodies in domestic animals in Turkey. Journal of Veterinary Medical Science, 2017, 78(12): 1877-1881.
   (4)  Mo Zhou#, Shinuo Cao#, Yuzi Luo, Mingming Liu, Guanbo Wang, Paul Franck Adjou Moumouni, Charoonluk Jirapattharasate, Aiko Iguchi, Patrick Vudriko, Mohamad Alaa Terkawi, Mario L?wenstein, Angela Kern, Yoshifumi Nishikawa, Hiroshi Suzuki, Ikuo Igarashi, Xuenan Xuan*, Molecular identification and antigenic characterization of a merozoite surface antigen and a secreted antigen of Babesia canis (BcMSA1 and BcSA1). Parasites & Vectors. 2016, 9: 257.
   (5)  Mo Zhou#, Shinuo Cao#, Ferda Sevinc, Mutlu Sevinc, Onur Ceylan, Paul Franck Adjou Moumouni, Charoonluk Jirapattharasate, Mingming Liu, Guanbo Wang, Aiko Iguchi, Patrick Vudriko, Hiroshi Suzuki, Xuenan Xuan*, Molecular detection and genetic identification of Babesia bigemina, Theileria annulata, Theileria orientalis and Anaplasma marginale in Turkey, Ticks and Tick-borne Diseases, 2016, 7(1): 126-134.
   (6)  Ferda Sevinc#*, Shinuo Cao#, Xuenan Xuan, Mutlu Sevinc, Onur Ceylan, Identification and expression of Babesia ovis secreted antigen 1 and evaluation of its diagnostic potential in an enzyme-linked immunosorbent assay., Journal of Clinical Microbiology, 2015, 53(5): 1531-1536.
   (7)  Gabriel Oluga Aboge#, Shinuo Cao#, Mohamad Alaa Terkawi, Tatsunori Masatani, Younkyoung Goo, Mahmoud AbouLaila, Yoshifumi Nishikawa, Ikuo Igarashi, Hiroshi Suzuki, Xuenan Xuan*, Molecular Characterization of Babesia bovis M17 Leucine Aminopeptidase and Inhibition of Babesia Growth by Bestatin., The Journal of Parasitology, 2015, 101(5): 536-541.
   (8)  Shinuo Cao#, Gabriel Oluga Aboge, Mohamad Alaa Terkawi, Mo Zhou, Ketsarin Kamyingkird, Paul Franck Adjou Moumouni, Tatsunori Masatani, Ikuo Igarashi, Yoshifumi Nishikawa, Hiroshi Suzuki, Xuenan Xuan*, Mycophenolic acid,  mycophenolate mofetil,  mizoribine,  ribavirin,  and 7-nitroindole inhibit propagation of Babesia parasites by targeting inosine 5'-monophosphate dehydrogenase., Journal of Parasitology, 2014, 100(4): 522-526.
   (9)  Yuzi Luo#, Yan Li#, Shinuo Cao#, Mohamad Alaa Terkawi, Dinh Thi Bich Lan, Phung Thang Long, Longzheng Yu, Mo Zhou, Haiyan Gong, Houshuang Zhang, Jinlin Zhou, Naoaki Yokoyama,  Hiroshi Suzuki, Xuenan Xuan*, Molecular and seroepidemiological survey of Babesia bovis and Babesia bigemina infections in cattle and water buffaloes in the central region of Vietnam. Tropical Biomedicine, 2014, 31(3): 406-413.
   (10)  Shinuo Cao, Gabriel Oluga Aboge, Mohamad Alaa Terkawi, Mo Zhou, Yuzi Luo, Longzheng Yu, Yan Li, Younkyoung Goo, Ketsarin Kamyingkird, Tatsunori Masatani, Hiroshi Suzuki, Ikuo Igarashi, Yoshifumi Nishikawa, Xuenan Xuan*, Cloning, characterization and validation of inosine 5′-monophosphate dehydrogenase of Babesia gibsoni as molecular drug target. Parasitology International, 2013, 62(2): 87-94.
   (11)  Shinuo Cao, Yuzi Luo, Gabriel Oluga Aboge, Mohamad Alaa Terkawi, Tatsunori Masatani, Hiroshi Suzuki, Ikuo Igarashi, Yoshifumi Nishikawa, Xuenan Xuan*, Identification and characterization of an interspersed repeat antigen of Babesia microti (BmIRA). Experimental Parasitology, 2013, 133(3): 346-352.
   (12)  Ahmed Abdelmoniem Mousa#, Shinuo Cao#, Gabriel Oluga Aboge, Mohamad Alaa Terkawi, Ahmed El Kirdasy, Akram Salama, Mabrouk Attia, Mahmoud Aboulaila, Mo Zhou, Ketsarin Kamyingkird, Paul Franck Adjou Moumouni, Tatsunori Masatani, Sami Ahmed Abd El Aziz, Waheed Mohammed Moussa, Bayin Chahan, Shinya Fukumoto, Yoshifumi Nishikawa, Salah Sayed El Ballal, Xuenan Xuan*, Molecular characterization and antigenic properties of a novel Babesia gibsoni glutamic acid-rich protein (BgGARP). Experimental Parasitology, 2013, 135(2): 414-420.
   (13)  Shinuo Cao, Shoufa Zhang, Lijun Jia, Shujiang Xue, Longzheng Yu, Ketsarin Kamyingkird, Paul Franck Adjou Moumouni, Ahmed Abd El Moniem Moussa, Mo Zhou, Yuanming Zhang, Mohamad Alaa Terkawi, Tatsunori Masatani, Yoshifumi Nishikawa, Xuenan Xuan*, Molecular detection of Theileria species in sheep from northern China. Journal of Veterinary Medical Science, 2013, 75(9): 1227-1230.
   (14)  Shinuo Cao#, Ahmed Mousa#, Gabriel Aboge, Ketsarin Kamyingkird, Mo Zhou, Paul Moumouni, Mohamad Terkawi, Tatsunori Masatani, Yoshifumi Nishikawa, Hiroshi Suzuki, Shinya Fukumoto, Xuenan Xuan*, Prime-boost vaccination with plasmid DNA followed by recombinant vaccinia virus expressing BgGARP induced a partial protective immunity to inhibit Babesia gibsoni proliferation in dogs. Acta Parasitologica, 2013, 58(4): 619-623.
   (15)  Shinuo Cao, Gabriel Oluga Aboge, Mohamad Alaa Terkawi, Longzheng Yu, Ketsarin Kamyingkird, Yuzi Luo, Yan Li, Youn-Kyoung Goo, Junya Yamagishi,  Yoshifumi Nishikawa, Naoaki Yokoyama, Hiroshi Suzuki, Ikuo Igarashi, Ryuichiro Maeda, Tawin Inpankaew, Sathaporn Jittapalapong, Xuenan Xuan*, Molecular detection and identification of Babesia bovis and Babesia bigemina in cattle in northern Thailand. Parasitology Research, 2012, 111(3): 1259-1266.
 
7、专利和标准
   (1) Shinuo Cao, Xuenan Xuan, Igarashi, Ikuo, Compounds and methods for the diagnosis of babesia canis canis infection. 欧洲专利 EP 2626365 A1. 2013, 8, 14.
 
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