Shou-Ping Hu,Zhuo Zhang,Fei Xiao,Jia-Ni Huang,Yan Jiang,Dong-Sheng Mao,Jing-Fei Wang,Xi-Jun He

J Comp Pathol.2022 Jul;195:1-6.doi: 10.1016/j.jcpa.2022.04.002. Epub 2022 May 16.

Case Reports

Abstract

A 3-year-old male Bichon Frise developed lethargy, anorexia and haematuria. B-scan ultrasonography examination revealed a small, irregular, soft-textured mass in the bladder. Histopathologically, there was an incomplete fibrous pseudocapsule around the tumour tissue and although there was clear demarcation from the surrounding tissue, there was invasion of the capsule. Tumour cells proliferated in nests or cords of variable size, separated by fibrovascular tissue. The neoplastic cells were immunopositive for chromogranin A, synaptophysin and neuron-specific enolase, and electron microscopy revealed that they contained cytoplasmic secretory granules. On the basis of these findings, the tumour was diagnosed as a primary paraganglioma of the urinary bladder.

Keywords: dog; neoplasia; paraganglioma; urinary bladder.

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