人才队伍

当前位置: 首页» 人才队伍» 青年英才

青年英才

李 海

 

1、个人简历
李海,男,博士,研究员,博士/硕士生导师,禽呼吸道传染病创新团队,中国农业科学院“青年英才计划”A类入选人,哈尔滨市科技创新人才“优秀学科带头人”,主要致力于病原与宿主互作机制研究,承担项目4项,发表文章17篇,现已招收培养研究生4人。

 
2、联系方式
(1)研究方向:兽医微生物及其分子生物学
(2)电话:0451-51051700
(3)邮箱:lihai@caas.cn
(4)通讯地址:黑龙江省哈尔滨市香坊区哈平路678号
 
3、教育经历 
1999.09-2004.06  沈阳农业大学      动物医学专业              学士
2004.09-2009.06  中国农业大学      动物遗传育种与繁殖专业    博士
2008.06-2014.05  卡罗林斯卡医学院  医学专业                  博士
 
4、工作经历
2014.09-今       中国农科院哈尔滨兽医研究所                  研究员
 
5、承担项目
1).“十三五” 国家重点研发计划项目:坦布苏病毒体液免疫应答宿主决定机制研究(2016YFD0500107-4,2016.07-2020.12), 127万元;
2). 哈尔滨市科技局项目:禽疱疹病毒I型宿主偏嗜性相关抗病毒靶标分子的筛选(2016RAXYJ072,2016.09-2019.09), 15万元;
3). 中央级公益性科研院所基本科研业务专项:鸡传染性喉气管炎病毒细胞毒作用宿主细胞依赖的分子机制的研究(1610302015003,2015.01-2017.12), 147.96万元;
 
6、代表论文与著作
1. Yu Zhang, Chenyang Zhua, Bangyao Sun, Jiawei Lv, Zhonghua Liu, Shengwang Liu, Hai Li. Integrated high throughput analysis identifies GSK3 as a determinant of p53-mediated apoptosis in lung cancer cells. Cell Physiol Biochem. 2017;42:1177-91. 
2. Li H, Wang F, Han Z, Gao Q, Li H, Shao Y, Sun N, Liu S. Genome-wide gene expression analysis identifies the proto-oncogene tyrosine-protein kinase Src as a crucial virulence determinant of the infectious laryngotracheitis virus in chicken cells. J. Virol. 2015;90(1):9-21. 
3. Hai Li, Yu Zhang, Anda Str?se, Yao Shi, Donato Tedesco, Katerina Gurova, Galina Selivanova. Integrated high throughput analysis identifies Sp1 as a crucial determinant of p53-mediated apoptosis. Cell Death Differ. 2014 June 27. 
4. Hai Li, Lakshmikanth Tadepally, Ennio Carbone, and Galina Selivanova. A novel facet of tumor suppression by p53: induction of tumor immunogenicity. Oncoimmunology. 2012 Jul 1;1(4):541-543.
5. Li H, Lakshmikanth T, Garofalo C, Enge M, Spinnler C, Anichini A, Szekely L, K?rre K, Carbone E, Selivanova G. Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2. Cell Cycle. 2011 Oct 1;10(19):3346-58. 
6. Hai Li, Yu Zhang, Shifeng Zuo, Zhengxing Lian and Ning Li. Effects of methyltestosterone on immunity against Salmonella Pullorum in dwarf chicks. Poult Sci. 2009 Dec 88(12):2539-48. 
7. Hai Li, Yu Zhang, Zhonghua Ning, Xuemei Deng, Zhengxing Lian and Ning Li. Effect of selection for phagocytosis in dwarf chickens on immune and reproductive characters. Poult. Sci. 2008 87:41-49.
8. Nikulenkov F, Spinnler C*, Li H*, Tonelli C, Shi Y, Turunen M, Kivioja T, Ignatiev I, Kel A, Taipale J, Selivanova G. Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis. Cell Death Differ. 2012 Dec;19(12):1992-2002. (*同等贡献) 
9. Spinnler C, Hedstr?m E, Li H, de Lange J, Nikulenkov F, Teunisse AF, Verlaan-de Vries M, Grinkevich V, Jochemsen AG, Selivanova G. Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX. Cell Death Differ. 2011 Nov 18(11):1736-45. 
10. Shi Y, Nikulenkov F, Zawacka-Pankau J, Li H, Gabdoulline R, Xu J, Eriksson S, Hedstr?m E, Issaeva N, Kel A, Arnér E, Selivanova G. ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis. Cell Death Differ. 2014 Apr 21(4):612-23. 
 
扫一扫 关注我
网站首页 联系我们
TOP