Dongsheng Mao,Xudong Song,Dexing Ma,Shouping Hu,Zhuo Zhang,Jingfei Wang,Xijun He

J Comp Pathol.2023 Nov 4:207:45-49.doi: 10.1016/j.jcpa.2023.10.003. Online ahead of print.

Abstract

An 11-year-old female Collie presented with a significantly increased abdominal circumference. Computed tomography of the abdomen revealed that the left lateral lobe of the liver contained a large mass, which was excised via laparotomy. Histologically, many small, dilated, cystic luminal structures were anastomosed and connected to a net-like structure. Immunohistochemistry revealed cytokeratin 19-immunopositive areas, representing bile duct structures in the cystic lumen. Based on these results, the tumour was diagnosed as a bile duct hamartoma. To our knowledge, this is the first report of a bile duct hamartoma in a dog.

Keywords: bile duct; dog; hamartoma; liver; von Meyenburg complex-like tumour.