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团队成员

陈普成

1、个人简历

    陈普成,男,博士,副研究员,硕士生导师,动物流感基础与防控研究创新团队研究助理,主要从事禽流感疫苗免疫机理研究及高致病性禽流感新型疫苗的开发和应用。承担项目有国家自然科学基金、兽医生物技术国家重点实验室自主课题等。在Journal of VirologyAntiviral Res.Vaccine等杂志发表多篇文章。

 

2、联系方式    

1研究方向:兽医微生物及其分子生物学

2电话:045151051679

3)邮箱:chenpucheng@caas.cn

4)所在单位:中国农业科学院哈尔滨兽医研究所

5)通讯地址:黑龙江省哈尔滨市香坊区哈平路678

 

3、教育经历

2002.09-2006.06  西北农林科技大学 动物科学专业 学士

2006.09-2009.06  中国农业科学院研究生院 预防兽医专业 硕士

2009.09-2012.06  中国农业科学院研究生院 预防兽医专业 博士

 

4、工作经历

2012.07-至今       中国农科院哈尔滨兽医研究所          

 

5、承担项目

   1. 国家自然基金青年基金项目,31402212,流感病毒以巨胞饮方式入侵细胞的研究,2015/01-2017/12,22万元,结题,主持

   2. 兽医生物技术国家重点实验室自主课题:(2018.01-2019.12),25 

 

6、代表论文与著作

1. Chen, P. C#., Liu, J. X., Jiang, Y. P., Zhao, Y. H., Li, Q. M., Wu, L., He, X. J., Chen, H. L*.,  The vaccine efficacy of recombinant duck enteritis virus expressing secreted E with or without PrM proteins of duck tembusu virus. Vaccine 2014.32, 5271-5277.

2. Liu, J. X#., Chen, P. C#., Jiang, Y. P., Deng, G. H., Shi, J. Z., Wu, L., Lin, Y., Bu, Z. G., Chen, H. L*.,  Recombinant duck enteritis virus works as a single-dose vaccine in broilers providing rapid protection against H5N1 influenza infection. Antiviral research 2013.97, 329-333.

3. Liu, J. X#., Chen, P. C#., Jiang, Y. P., Wu, L., Zeng, X. Y., Tian, G. B., Ge, J. Y., Kawaoka, Y., Bu, Z. G., Chen, H. L*.,  A Duck Enteritis Virus-Vectored Bivalent Live Vaccine Provides Fast and Complete Protection against H5N1 Avian Influenza Virus Infection in Ducks. Journal of virology 2011.85, 10989-10998.

4. Zeng, X. Y#., Chen, P. C., Liu, L. L., Deng, G. H., Li, Y. B., Shi, J. Z., Kong, H. H., Feng, H. P., Bai, J., Li, X., Shi, W. J., Tian, G. B., Chen, H. L*.,. Protective Efficacy of an H5N1 Inactivated Vaccine Against Challenge with Lethal H5N1, H5N2, H5N6, and H5N8 Influenza Viruses in Chickens. Avian diseases 60, 2016a 253-255.

5. Zeng, X. Y#., Deng, G. H., Liu, L. L., Li, Y. B., Shi, J. Z., Chen, P. C., Feng, H. P., Liu, J. L., Guo, X. F., Mao, S. G., Yang, F., Chen, Z. Y., Tian, G. B., Chen, H. L*.,. Protective Efficacy of the Inactivated H5N1 Influenza Vaccine Re-6 Against Different Clades of H5N1 Viruses Isolated in China and the Democratic People's Republic of Korea. Avian diseases 2016b 60, 238-240.

6. Liu, L#., Zeng, X., Chen, P., Deng, G., Li, Y., Shi, J., Gu, C., Kong, H., Suzuki, Y., Jiang, Y., Tian, G., Chen, H*., Characterization of Clade 7.2 H5 Avian Influenza Viruses That Continue to Circulate in Chickens in China. Journal of virology. 2016.

7. Zhao, Y. H#., Wang, X. R., Chen, P. C., Zeng, X. Y., Bao, H. M., Wang, Y. H., Xu, X. L., Jiang, Y. P., Chen, H. L., Li, G. X*., Detection of antibodies against avian influenza virus by protein microarray using nucleoprotein expressed in insect cells. Journal of Veterinary Medical Science  2015.77, 413-419

8. Wu, L#., Liu, J. X., Chen, P. C., Jiang, Y. P., Ding, L. L., Lin, Y., Li, Q. M., He, X. J., Chen, Q. S., Chen, H. L*., The Sequential Tissue Distribution of Duck Tembusu Virus in Adult Ducks. BioMed research international. 2014.

9. Zhang, Q. Y#., Shi, J. Z#., Deng, G. H#., Guo, J#., Zeng, X. Y., He, X. J., Kong, H. H., Gu, C. Y., Li, X. Y., Liu, J. X., Wang, G. J., Chen, Y., Liu, L. L., Liang, L. B., Li, Y. Y., Fan, J., Wang, J. L., Li, W. H., Guan, L. Z., Li, Q. M., Yang, H. L., Chen, P. C., Jiang, L., Guan, Y. T., Xin, X. G., Jiang, Y. P., Tian, G. B., Wang, X. R., Qiao, C. L., Li, C. J., Bu, Z. G., Chen, H. L*., H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet. Science 2013. (New York, N.Y 341, 410-414.

 

7、专利和标准

1. 表达H5亚型禽流感病毒HA基因重组火鸡疱疹病毒,专利号:201410024770.X(第2完成人)

2.表达分泌型鸭坦布苏病毒E蛋白的重组鸭病毒性肠炎病毒疫苗的构建和应用,专利号:ZL201210331134.2(第3完成人)

3.表达分泌型鸭坦布苏病毒ME蛋白的重组鸭病毒性肠炎病毒疫苗的构建和应用,专利号:ZL201210331133.8(第3完成人)

4.编码H5N1亚型禽流感同义血凝素(HA)蛋白及同义神经氨酸酶(NA)蛋白的基因及其应用,专利号:ZL201310322448.0(第5完成人)

 

8、获得奖励

   1. 动物流感病毒引起人流感大流行的潜力及其遗传机制,中国农业科学院杰出科技创新奖(第13完成人),2015

 

(2019年6月更新)

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