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团队成员

杨焕良

 
1、个人简历
杨焕良,男,博士,副研究员,硕士研究生导师,动物流感基础与防控创新研究团队,猪流感分子流行病学、诊断方法以及疫苗研究,承担国家重点研发计划项目、国家自然科学基金、黑龙江省自然科学基金等20项以上,在PNAS,JVI,Science,Cell research等中英文期刊发表科技论文60篇以上;起草国家标准3项;获得国家发明专利2项;获得黑龙江科技进步二等奖1项,中国农业科学院杰出科技创新奖1项。


 
2、联系方式
(1)研究方向:动物传染病及其病原分子流行病学
(2)电话:0451-51051675
(3)邮箱:yanghuanliang@caas.cn
(4)通讯地址:黑龙江省哈尔滨市哈平路678号
 
3、教育经历 
1995.09-1999.06 中国农业大学 兽医专业 学士
2002.09-2005.06 东北农业大学 预防兽医专业 硕士
2010.09-2013.06 中国农业科学院研究生院 预防兽医专业 博士
 
4、工作经历
1999.07-2004.12 中国农科院哈尔滨兽医研究所 研究实习员
2005.01-2014.12 中国农科院哈尔滨兽医研究所 助理实习员
2015.01-              中国农科院哈尔滨兽医研究所 副研究员
 
5、承担项目
(1)“十三五” 国家重点研发计划项目:动物流感病毒生态学与遗传变异(2016YFD0500201,2016.07-2020.12),100万元,课题骨干;
(2) 黑龙江省自然科学基金(面上项目):《H1N1亚型猪流感病毒跨猪-人宿主传播机制研究》。(C2016066,2016.06-2019.06),6万元,项目负责人;
(3) 中央级公益性科研院所基本科研业务费专项,猪流感病毒分子流行病学与及疫苗候选株的筛选(1610302015011,2015.01-2016.12),78.48万元,项目负责人;
(4) FAO国际合作EPT+项目,FAO中国猪流感流行病学(CHN/2013/001/LOA,2013.01-2013.08),120.54万元,项目负责人;
(5) 国家重点实验室开放课题,免疫压力下流感病毒变异规律的研究(SKLVBP201209,2012.01-2013.12),15万元,项目负责人。
 
6、代表论文与著作
(1)Wang Z#, Yang H#, Chen Y, Tao S, Liu L, Kong H, Ma S, Meng F, Suzuki Y, Qiao C, Chen H*. 2017. A Single-Amino-Acid Substitution at Position 225 in HA Alters the Transmissibility of Eurasian Avian-like H1N1 Swine Influenza Virus in Guinea Pigs. Journal of virology.
(2)Yang H, Chen Y, Qiao C, He X, Zhou H, Sun Y, Yin H, Meng S, Liu L, Zhang Q, Kong H, Gu C, Li C, Bu Z, Kawaoka Y, Chen H*. 2016. Prevalence, genetics, and transmissibility in ferrets of Eurasian avian-like H1N1 swine influenza viruses. Proceedings of the National Academy of Sciences of the United States of America 113:392-397.
(3)Yang H, Chen Y, Qiao C, Xu C, Yan M, Xin X, Bu Z, Chen H*. 2015. Two different genotypes of H1N2 swine influenza virus isolated in northern China and their pathogenicity in animals. Veterinary microbiology 175:224-231.
(4)Wu Y, Qiao C*, Yang H, Chen Y, Xin X, Chen H. 2014. Immunogenicity and efficacy of a recombinant adenovirus expressing hemagglutinin from the H5N1 subtype of swine influenza virus in mice. Canadian journal of veterinary research 78:117-126.
(5)Qiao C, Liu L, Yang H, Chen Y, Xu H, Chen H*. 2014. Novel triple reassortant H1N2 influenza viruses bearing six internal genes of the pandemic 2009/H1N1 influenza virus were detected in pigs in China. Journal of clinical virology 61:529-534.
(6)Chen Y, Zhang J, Qiao C*, Wang J, Yang H, Chen H*. 2014. Identification of a linear epitope on the haemagglutinin protein of pandemic A/H1N1 2009 influenza virus using monoclonal antibodies. Archives of virology 159:1413-1419.
(7)Zhang Q, Shi J, Deng G, Guo J, Zeng X, He X, Kong H, Gu C, Li X, Liu J, Wang G, Chen Y, Liu L, Liang L, Li Y, Fan J, Wang J, Li W, Guan L, Li Q, Yang H, Chen P, Jiang L, Guan Y, Xin X, Jiang Y, Tian G, Wang X, Qiao C, Li C, Bu Z, Chen H*. 2013. H7N9 influenza viruses are transmissible in ferrets by respiratory droplet. Science 341:410-414.
(8)Chen Y, Zhang J, Qiao C, Yang H, Zhang Y, Xin X, Chen H*. 2013. Co-circulation of pandemic 2009 H1N1, classical swine H1N1 and avian-like swine H1N1 influenza viruses in pigs in China. Infection, genetics and evolution 13:331-338.
(9)Yang H, Qiao C, Tang X, Chen Y, Xin X, Chen H*. 2012. Human infection from avian-like influenza A (H1N1) viruses in pigs, China. Emerging infectious diseases 18:1144-1146.
(10)Yang H, Chen Y, Shi J, Guo J, Xin X, Zhang J, Wang D, Shu Y, Qiao C, Chen H. 2011. Reassortant H1N1 influenza virus vaccines protect pigs against pandemic H1N1 influenza virus and H1N2 swine influenza virus challenge. Veterinary microbiology 152:229-234.
(11)Xu C, Zhu Q, Yang H, Zhang X, Qiao C, Chen Y, Xin X, Chen H*. 2009. Two genotypes of H1N2 swine influenza viruses appeared among pigs in China. Journal of clinical virology: 46:192-195.
(12)Zhu Q, Yang H, Chen W, Cao W, Zhong G, Jiao P, Deng G, Yu K, Yang C, Bu Z, Kawaoka Y, Chen H*. 2008. A naturally occurring deletion in its NS gene contributes to the attenuation of an H5N1 swine influenza virus in chickens. Journal of virology 82:220-228.
 
7、专利和标准
(1)杨焕良,陈化兰,陈艳,乔传玲. 重组类禽型H1N1流感病毒灭活疫苗株(JS40/PR8)的制备及应用,中国,ZL 201410460909.5 
(2)乔传玲,吴运普,杨焕良,陈艳,辛晓光,陈化兰. 一种重组复制缺陷型腺病毒载体H5N1亚型流感基因工程疫苗,中国ZL 2008 1 0239333.4;
(3)乔传玲,韩雪清,杨焕良,刘业兵,陈艳,吴绍强,陈化兰,林祥梅,辛晓光,朱中武,朱中武,王慧煜,刘建,李建,梅琳,王伊琴,徐彪,阮周曦,宁宜宝,薄清如,秦智锋,林志雄,国家标准 GB/T 27535-2011猪流感HI抗体检测方法,中国,2011/11/21
(4)乔传玲,杨焕良,陈艳,辛晓光,陈化兰,国家标准 GB/T27536-2011猪流感病毒分离与鉴定方法,中国, 2011/11/21
(5)乔传玲,杨焕良,陈艳,辛晓光,陈化兰,国家标准 GB/T27535-2011猪流感HI抗体检测方法,中国, 2011/11/21
 
8、获得奖励
(1)禽流感酶联免疫吸附试验诊断技术的研究及应用,黑龙江省科学技术二等奖,于康震,李海燕、辛晓光、杨林、邓国华、杨焕良、田国彬、李书华、王秀荣,2005年。
 
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