1、个人简历

钟功勋，男，博士，研究员，博士生导师，重要人兽共患病与烈性外来病创新团队，中国农业科学院“青年英才”。一直致力于新型冠状病毒感染、裂谷热、流感等烈性人兽共患传染病研究，近年来作为团队骨干参与新冠病毒动物易感性、动物感染模型的建立和应用等方面的研究，并取得突破性进展，于2021年获科技部“全国科技系统抗击新冠肺炎疫情先进个人”表彰。以第一或通讯（含共同）作者在Science、National Science Review、Nature Communications、Protein & Cell、Emerging Infectious Diseases、Journal of Virology等杂志发表SCI论文12篇，累计影响因子182。

2、联系方式

电话：0451-51051815

电子邮箱：zhonggongxun@caas.cn

通讯地址：哈尔滨市香坊区哈平路678号

3、教育经历

1999.09 – 2003.07 浙江大学动物科学专业 学士

2004.09 – 2007.07 中国农业科学院研究生院预防兽医专业 硕士

2007.09 – 2010.07 中国农业科学院研究生院预防兽医专业 博士

4、工作经历

2010.09 – 2019.05 美国威斯康辛大学麦迪逊分校 博士后，助理科学家

2019.06 – 至今 中国农业科学院哈尔滨兽医研究所重要人兽共患病与烈性外来病团队，研究员

5、代表性论文与著作

1. Shi J#, Wen Z#, Zhong G#, Yang H#, Wang C#, Huang B#, Liu R, He X, Shuai L, Sun Z, Zhao Y, Liu P, Liang L, Cui P, Wang J, Zhang X, Guan Y, Tan W, Wu G*, Chen H*, Bu Z*.  Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2.  Science  2020, 368:1016-1020.

2. Zhao M#, Zhu Y#, Zhang L#, Zhong G#, Tai L, Liu S, Yin G, Lu J, He Q, Li, M, Zhao R, Wang H, Huang W, Fan C, Shuai L, Wen Z, Wang C, He X, Chen Q, Liu B, Xiong X, Bu Z#, Wang Y*, Sun F* and Yang J*. Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies.  Cell Discov  ery  2022, 8(1):53.

3. Wang J#, Shuai L#, Wang C#, Liu R#, He X, Zhang X, Sun Z, Shan D, Ge J, Wang X, Hua R, Zhong G*, Wen Z*, Bu Z*. Mouse-adapted SARS-CoV-2 replicates efficiently in the upper and lower respiratory tract of BALB/c and C57BL/6J mice.  Protein Cell  2020, 11(10):776-782.

4. Wu S#, Zhong G#, Zhang J#, Shuai L#, Zhang Z, Wen Z, Wang B, Zhao Z, Song X, Chen Y, Liu R, Fu L, Zhang J, Guo Q, Wang C, Yang Y, Fang T, Lv P, Wang J, Xu J, Li J, Yu C, Hou L*, Bu Z*, Chen W*. A single dose of an adenovirus-vectored vaccine provides protection against SARS-CoV-2 challenge.  Nature Communications  2020, 11:4081.

5. Shuai L#, Zhong G#, Yuan Q#, Wen Z#, Wang C#, He X#, Liu R, Wang J, Zhao Q, Liu Y, Huo N, Deng J, Bai J, Wu H, Guan Y, Shi J, Tian K, Xia N, Chen H*, Bu Z*. Replication, pathogenicity, and transmission of SARS-CoV-2 in minks.  National Science Review  2021, 8(3):nwaa291.

6. Zhong G, Fan S, Hatta M, Nakatsu S, Walters KB, Lopes TJS, Wang JIH, Ozawa M, Karasin A, Li Y, Tong SX, Donis RO, Neumann G*, Kawaoka Y*. Mutations in the Neuraminidase-Like Protein of Bat Influenza H18N11 Virus Enhance Virus Replication in Mammalian Cells, Mice, and Ferrets.  J Virol  2020, 94:e01416-19.

7. Zhong G#, Fan S#, Lopes TJS, Le MQ, van Bakel H, Dutta J, Smith GJD, Jayakumar J, Nguyen HLK, Hoang PVM, Halfmann P, Hatta M, Su YCF, Neumann G*, Kawaoka Y*. Isolation of Highly Pathogenic H5N1 Influenza Viruses in 2009-2013 in Vietnam.  Front Microbiol  2019, 10:1411.

8. Watanabe T#, Zhong G#, Russell CA#, Nakajima N, Hatta M, Hanson A, McBride R, Burke DF, Takahashi K, Fukuyama S, Tomita Y, Maher EA, Watanabe S, Imai M, Neumann G, Hasegawa H, Paulson JC, Smith DJ, Kawaoka Y*. Circulating avian influenza viruses closely related to the 1918 virus have pandemic potential.  Cell Host Microbe  2014, 15(6):692-705.

9. Zhong G, Le MQ, Lopes T, Halfmann P, Hatta M, Fan S, Neumann G*, and Kawaoka Y*. Mutations in the PA Protein of Avian H5N1 Influenza Viruses Affect Polymerase Activity and Mouse Virulence.  J Virol  2018, 92(4): e01557-17.

10. Hatta M#, Zhong G#, Gao Y#, Nakajima N#, Fan S#, Chiba S, Deering K, Ito M, Imai M, Kiso M, Nakatsu S, Lopes T, Thompson A, McBride R, Suarez D, Macken C, Sugita S, Neumann G, Hasegawa H, Paulson J, Toohey-Kurth K, and Kawaoka Y*. Characterization of a Feline Influenza A(H7N2) Virus.  Emerg Infect Dis  2018, 24(1),75-86.

11. Li Y#, Shi J#, Zhong G#, Deng G#, Tian G, Ge J, Zeng X, Song J, Zhao D, Liu L, Jiang Y, Guan Y, Bu Z, Chen H*. Continued evolution of H5N1 influenza viruses in wild birds, domestic poultry and humans in China from 2004 to 2009.  J Virol  2010, 84(17):8389-97.

12. Tang Y#, Zhong G#, Zhu L#, Liu X, Shan Y, Feng H, Bu Z, Chen H*, and Wang C*. Herc5 attenuates influenza A virus by catalyzing ISGylation of viral NS1 protein.  J Immunol  2010, 184(10):5777-90.

6、获得奖励 

2021年获科技部“全国科技系统抗击新冠肺炎疫情先进个人”表彰。